L-type (Loaf) Cervical Secretion Crystallization Directionality Biomarker Study

Background: Cervical discharge is considered a hydrogel, which part liquid and solid. Under physiological conditions, the characteristic “fern-leaf” arborization proportional to circulating estradiol concentration maximal in preovulatory phase. Crystallization of cervical secretion process dehydration with arrangement sodium potassium chloride crystals around main axis composed mucin. L-type (Loaf) (L) higher Fertile Window (FW). Currently, most studies comparing FW include biophysical fertile window (BFW) 6 days before estimated day ovulation (EDO). Methods: Samples were taken from vulvovaginal region within using Creighton Model System for Fertility Care (CrMS). Optical images samples digitized perform binarization, skeletonization, crystallization directionality study scanned branches. These not collected endocervix. They recorded by Vaginal Secretion Recording (VDRS) CrMS. The was into account peak (P) according CrMS.A statistical performed including –6 EDO FW. Results: Out 29 samples, 58.6% deemed true positives, 34% negatives, 6.8% represented 2 false no cases negatives (p < 0.001). Conclusions: Our analysis distribution branching angles secretions allowed us detect significant contribution 90-degree frecuencies, indicating, existence an pattern that we studied. skeletonization studied together indicator identify this pattern. We therefore propose feature detection mechanism as novel biomarker fertility.